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A comprehensive curated resource for follicle stimulating hormone signaling
A comprehensive map of the influenza A virus replication cycle
A comprehensive map of the mTOR signaling network.
A comprehensive map of the toll-like receptor signaling network
A comprehensive molecular interaction map of the budding yeast cell cycle
A computational analysis of the dynamic roles of talin, Dok1, and PIPKI for integrin activation.
A delay-differential equation model of the feedback-controlled hypothalamus-pituitary-adrenal axis in humans
A mathematical model of the human menstrual cycle for the administration of GnRH analogues.
A mathematical model of the regulation system of the secretion of glucocorticoids
A model for the dynamics of human weight cycling.
A model of gonadotropin regulation during the menstrual cycle in women: qualitative features
A model-based approach to the in vitro evaluation of anticancer activity.
A multiscale model of interleukin-6-mediated immune regulation in Crohn's disease and its application in drug discovery and development.
A multiscale model to investigate circadian rhythmicity of pacemaker neurons in the suprachiasmatic nucleus
A one-hit model of cell death in inherited neuronal degenerations.
A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients
A quantitative description of membrane current and its application to conduction and excitation in nerve. (SBML l3v1)
A semi-mechanistic model of the relationship between average glucose and HbA1c in healthy and diabetic subjects.
A synthetic Escherichia coli predator–prey ecosystem
A theoretical study on activation of transcription factor modulated by intracellular Ca2+ oscillations.
A whole-body mathematical model of cholesterol metabolism and its age-associated dysregulation.
Application of Petri net theory for modelling and validation of the sucrose breakdown pathway in the potato tuber.
Approximate model of cooperative activation and crossbridge cycling in cardiac muscle using ordinary differentialequations.
CA1 Pyramidal Cell
CA1 pyramidal cell - Ferguson et al. 2014
Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation
Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death.
Complete network of the Bhalla-Iyengar model
Computational Model for Effects of Ligand/Receptor Binding Properties on Interleukin-2 Trafficking Dynamics and T Cell Proliferation Response
Computational model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons
Constraint-based modeling and kinetic analysis of the Smad dependent TGF-beta signaling pathway.
Construction of a genetic toggle switch in Escherichia coli.
Dynamical modeling of the cholesterol regulatory pathway with Boolean networks.
Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance.
FAAH inhibitors for the treatment of osteoarthritic pain
Full-scale model of glycolysis in Saccharomyces cerevisiae
HIV latency. Interaction between HIV proteins and immune response
HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time
Hodgkin Huxley Tutorial (NeuroMl 2)
Hodgkin, Huxley, 1952 (CellML 1.1)
Integrating life history and cross-immunity into the evolutionary dynamics of pathogens.
MacNamara2012 - Signal transduction
Mathematical model of the cell division cycle of fission yeast
Mathematical model predicts a critical role for osteoclast autocrine regulation in the control of bone remodeling.
Mathematical modeling and analysis of force induced bone growth
Mathematical modeling and analysis of insulin clearance in vivo.
Metabolic Modeling and Simulation Analysis of Thyroid Disorder Pathway
Mitochondrial Modulation of Intracellular Ca2+ Signalling
Modeling the control of DNA replication in fission yeast.
Modeling the intracellular dynamics of influenza virus replication to understand the control of viral RNA synthesis.
Modelling and experimental analysis of hormonal crosstalk in Arabidopsis.
Multiple light inputs to a simple clock circuit allow complex biological rhythms
Nonlinearities make a difference: comparison of two common Hill-type models with real muscle
Overgaard, Holford, Rytved, Madsen, 2007
PKPD behaviour - 5-Lipoxygenase inhibitors
Population-Based Analysis of Methadone Distribution and Metabolism Using an Age-Dependent Physiologically Based Pharmacokinetic Model
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth after administration of an anti-angiogenic agent, bevacizumab, as single-agent and combination therapy in tumor xenografts.
Quantification of short term signaling by the epidermal growth factor receptor.
Stortelder1997 - Thrombin Generation Amidolytic Activity
Switching from simple to complex oscillations in calcium signaling.
Systematic construction of kinetic models from genome-scale metabolic networks.
Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection.
T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes.
Terfve2012 - Signalling in liver cancer - logical model
Vaccination and the dynamics of immune evasion
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The Lotka–Volterra equations, also known as the predator–prey equations, are a pair of first-order, non-linear, differential equations frequently used to describe the dynamics of biological systems in which two species interact, one a predator and one its prey. They were proposed independently by Alfred J. Lotka in 1925 and Vito Volterra in 1926. This model is parameterised as follows: x = 3, y = 6, A = 1, B = 1, C = 1, D = 1.