Standard Formats

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PharmML v0.6


Pharmacometrics Markup Language Version 0.6

Synopsis

Format for exchange of pharmacometric models.

Description

The lack of a common exchange format for mathematical models in pharmacometrics has been a long-standing problem. Such a format has the potential to increase productivity and analysis quality, simplify the handling of complex workflows, ensure reproducibility of research, and facilitate the reuse of existing model resources. Pharmacometrics Markup Language (PharmML), currently under development by the Drug Disease Model Resources (DDMoRe) consortium, is intended to become an exchange standard in pharmacometrics by providing means to encode models, trial designs, and modeling steps.*

*(Swat M et al.. CPT: Pharmacometrics & Systems Pharmacology. 2015;4(6):316-319.)

Publication Date

01/2015

Authors

Moodie, Stuart
Le Novère, Nicolas
J. Swat, Maciej
Wimalaratne, Sarala
Rode Kristensen, Niels
Yvon, Florent

Organizations


Biological Scales

Scale molecular cellular tissue organ organism ecosystem
Support unknown intrinsic intrinsic intrinsic intrinsic unknown

Spatial Representation

Spatial Representation Level Compartment Dimensions Gradients Spatial Structures
Support intrinsic unknown unknown unknown

Modeling Formalisms for this format

Software support for this format

Examples for this format


Advantage

  • Extensible XML scheme
  • Interfacing NONMEM/Monolix datasets
  • Interfacing UncertML
  • Intrinsic Simulation Experiment Description
  • Vector/Matrices Support

Modularity: yes


Components Relation
Flat Network: no


Supported Math

MathML Support: no

Full MathML Support: no

Description

Own mathematical definitions. Support of expression validation.


Unit Support

Unit Required: no

Support: intrinsic

Description

Units are handled as metadata and as any annotations are supposed to be stored in an external RDF file.

Annotation Support

Miriram Support: no

identifiers.org Support: yes

Description

Any annotations is supposed to be stored in an external RDF file.


There are no transformations available!

libPharmML


Programming language

Java

Links

libPharmML


stand-alone pharmML validator


Pharmacometrics Markup Language (pharmML)


Description

Format for exchange of pharmacometric models.

Derived from

XML

Publication date

11/2013

Organizations

Links

Webpage

All formats for this class

Apache License , Version 2.0


Description

For exact licence information see webpage.

Links